Variable responses to transcranial direct current stimulation protocols across individuals are widely reported, but the reasons behind this variation are unclear. This includes tDCS protocols meant to improve attention. Attentional control is impacted by top-down and bottom-up processes, and this relationship is affected by state characteristics such as anxiety. According to Attentional Control Theory, anxiety biases attention towards bottom-up and stimulus-driven processing. The goal of this study was to explore the extent to which differences in state anxiety and related measures (...) affect visual attention and category learning, both with and without the influence of tDCS. Using discovery learning, participants were trained to classify pictures of European streets into two categories while receiving 30 min of 2.0 mA anodal, cathodal, or sham tDCS over the rVLPFC. The pictures were classifiable according to two separate rules, one stimulus and one hypothesis-driven. The Remote Associates Test, Profile of Mood States, and Attention Networks Task were used to understand the effects of individual differences at baseline on subsequent tDCS-mediated learning. Multinomial logistic regression was fit to predict rule learning based on the baseline measures, with subjects classified according to whether they used the stimulus-driven or hypothesis-driven rule to classify the pictures. The overall model showed a classification accuracy of 74.1%. The type of tDCS stimulation applied, attentional orienting score, and self-reported mood were significant predictors of different categories of rule learning. These results indicate that anxiety can influence the quality of subjects’ attention at the onset of the task and that these attentional differences can influence tDCS-mediated category learning during the rapid assessment of visual scenes. These findings have implications for understanding the complex interactions that give rise to the variability in response to tDCS. (shrink)

Rodger et al argue for the disenhancement of animals intended for xenotransplantation; that is, the transference of tissues or organs from one species to another. The crux of their claim is that the conditions necessary to facilitate xenotransplantation will be hostile to those subjected to them. Thus, to minimise the suffering of living under such conditions, ‘ethically defensible xenotransplantation should entail the use of genetic disenhancement if it becomes possible to do so and if that pain and suffering cannot be (...) eliminated by other means.’1 In other words, if we can eliminate or meaningfully reduce the suffering of animals destined for xenotransplantation by obliterating their experiential capacity and lacking a less contentious method to achieve the same result, we should do so. When isolated, this argument is compelling. Suffering is terrible and should be avoided. Additionally, when we have the option to reduce another’s suffering—be that human, animal or otherwise—there are strong prima facie arguments that we should do so. This point is reinforced when we collectively are responsible for that suffering, as would be the case with xenotransplantation, and it is true regardless of how justified we are in causing that suffering. Thus, on the restrictive terms of Rodger et al ’s argument, I agree with them. We should eliminate, or if not possible, reduce, suffering wherever we can, and this applies to animals too. Having said that, when situated in the xenotransplantation context, issues with their proposal …. (shrink)

In their paper, Hildt (2023) surveys several socio-ethical and regulatory issues arising from research into, and the potential emergence of, artificial consciousness—synthetic beings with a claim t...

In the poem which sets the seal on his three books of odes, Horace declares that his monument to himself will be more durable than bronze and higher than the pyramids. As T. E. Page noted in his commentary, aere can suggest not only bronze tablets, but also commemorative statuary, although tablets seems more to the fore here, given the reference to monumentum As for the pyramids, they are a fine example of grandiloquent architecture, but of a kind which is (...) nevertheless subject to the destructive natural forces from which Horace exempts his own commemoration. (shrink)

This is a confusing attempt to reconcile realist philosophy with an aesthetic stand. The book includes a discussion of the contributions of artists, philosophers, and critics to the formulation of an aesthetic viewpoint; a brief history of idealistic aesthetic theory embodied in the ideas of Kant, Hegel, Croce, and Tolstoy; a definition and defense of "excellence" as the criterion in the evaluation of art; and a justification for the continued inclusion of aesthetics as a philosophical endeavor. Realists, with their emphasis (...) on the scientific approach, verification, and measurement have always had a certain amount of understandable trouble with the arts, a field known for its fluidity and willful perversity regarding attempts to establish permanent, stable criteria of evaluation. Gibson draws heavily on Wittgenstein's idea of "family resemblances" and Weitz's application of that idea to art. In doing so, however, he ignores Weitz's warning that since art has no set of necessary properties and since, therefore, it is impossible to formulate theoretical definitions of it, aestheticians might better spend their time on other issues. Gibson builds his case around a family resemblance of various, so-called permanent excellences such as "significant form," "expressiveness," and "communicative efficacy" which, he insists, just happen to converge together in "great" works of art. With this statement, as well as others concerning the effect great art must produce in the beholder, Gibson has returned to the idea of an Absolute definition which, though pluralistic in scope, is still as rigid, exclusive, and closed a concept as the ones he denounces, despite his statements of "proof" to the contrary. Mention should also be made of the weakness of the overall structure of the book. Ideas and explanations become confusing when they are dropped in driblets throughout diverse chapters. This book adds nothing to the ideas of Wittgenstein or Weitz while, at the same time, detracting considerably from the clarity and logic of their concepts.--B. T. (shrink)

This work explores an aspect of Yeats's writing largely ignored until now: namely, his wide-ranging absorption in S.T. Coleridge. Gibson explores the consistent and densely woven allusions to Coleridge in Yeats's prose and poetry, often in conjunction with other Romantic figures, arguing that the earlier poet provided him with both a model of philosopher - 'the sage' - and an interpretation of metaphysical ideas which were to have a resounding effect on his later poetry, and upon his rewriting of (...) A Vision. (shrink)

Perspectives on Quine, now available in paperback, is a collection of twenty-one new essays dealing with the thought of America's most distinguished living philosopher, Willard Van Orman Quine. After the editors' brief introduction to Quine's thought, the volume opens with an important new essay by Quine entitled Three Indeterminacies. The essays that follow, written by leading philosophers, are rich with insights into a wide variety of Quine's concerns ranging from logic and set theory to natural language, truth, evidence, natural kinds, (...) naturalized epistemology, and much more. Each essay concludes with a summary and response from Quine himself. (shrink)

This collection of essays addresses some of the central issues in modern social and political thought, such as: the revival of Marxism and its relevance to the social sciences; the analysis of social and political structures and social movements; and the future of advanced capitalist societies.

The comic is one of the principal esthetic categories; it unites the multifaceted experience of the social mind as it assimilates and cognizes the world, particularly the social world, on the basis of axioms of common sense, or even of public opinion about these axioms. Boldly violating the laws of logic and the verisimilitude of images, of normal connections and notions, and playing upon these violations, the comic nonetheless remains firmly on the side of common sense. The comic is inexhaustible (...) in its nuances — from light merriment and entertainment to malicious ridicule and satire, from gross farce to subtle forms of irony and humor. (shrink)

In this paper we consider the effect of unitarity bounds sb⩾s≡(E1+E2) cms 2 for the recently proposed types of nonderivative 4-fermion contact interactions. To this purpose we decompose the helicity amplitudes at c.m.s. into partial waves. The bounds are defined to hold for all reaction channels due to the same type of contact interaction. We find sb=τ4π/κ. Here κ is the coupling constant. The factor τ depends on the type of coupling and on the different cases to identify the fermions. (...) It ranges from 1/3 to 4. (shrink)

In Martin v. Ortho Pharmacetrtical Corp. ), the Supreme Court of Illinois held that, although a federal regulation requires pharmaceutical manufacturers to provide direct warnings to consumers about the dangers associated with oral contraceptives, this regulation does not constitute an exception to the learned intermediary doctrine and the manufacture will not be held strictly liable. The court declined to recognize an exception for manufacturers of contraceptives due to important policy considerations and the legislative intent underlying the learned intermediary doctrine. The (...) doctrine is based on the assumption that prescribing physicians, not pharmaceutical manufacturers, are in the best position to provide direct warnings to patients concerning the dangers associated with prescription drugs. The decision may affect patients whose medical care providers are unable to account for drug propensities or patient susceptibilities. Additionally, patients with forgetful or inarticulate health care providers are at risk. (shrink)

The Court of Appeals of Minnesota, in State v. Saunders ), held that the statutory offense of practicing medicine without a license was not unconstitutionally vague as applied to a claim involving a farmer who offered a home remedy to cure cancer. The court held that, although Minnesota Statute § 147.081 subd. 3 contains general language and undefined terms, the statute contains sufficient particularity to show ordinary persons what conduct is prohibited, and thereby passes the void-for-vagueness test. The court stated (...) that, according to the statute, while a person holding a license to practice medicine is permitted to engage in a broad range of conduct, those without that license are proscribed from engaging in that same range of conduct.The defendant, Mr. Saunders, a dairy farmer, claimed that he could cure ill people by injecting an ill person's blood into a cow and then feeding that person the cow's colostrum. (shrink)

Thomas Bertram Lonsdale Webster. the Persians decided on the best form of government in 520 B.C., but it is far more likely that the discussion reflects political theorising at Athens where he was writing during the contest for power between ...